Kim and Alberto’s new preprint, “Diverse origins and transcriptional profiles of macrophages in a spinal lesion in zebrafish” is now live on bioRxiv! Check it out here!‍

Sofiia and Ana-Maria’s new preprint, “Tachykinin neuropeptides are involved in axonal and synaptic differentiation of the pioneer motor axon in zebrafish” is now live on bioRxiv! Check it out here!

Alberto’s paper examining how the rate of production of newborn neurons is controlled by microglia after spinal cord injury was accepted at PLOS Biology! Microglia use sema4ab to signal to both neural stem cells and fibroblasts to rate-limit the number of new neurons which are born to replace those lost after injury. Check out the paper here! The CMCB press release with more details about the background of the study is here!

Xiaobo’s paper examining how neutrophils regulate the inflammatory response after spinal cord injury was accepted at the Journal of Neuroinflammation! Neutrophils use Il-4 to signal to other immune cells, such as macrophages, to down-tune the pro-inflammatory response to injury. Check out the paper here! The CMCB press release with more details about the background of the study is here!

Xiaobo’s new preprint, “A reparative neutrophil subpopulation promotes spinal cord regeneration in zebrafish by controlling macrophage inflammation via Il-4” is now live on bioRxiv! Check it out here!

Alberto’s new preprint, “Microglia attenuate regenerative neurogenesis via sema4ab after spinal cord injury in zebrafish” is now live on bioRxiv! Check it out here!

A new collaborative preprint contributed to by Ana-Maria and Sofiia, “Altered lysosomal biology impairs motor neuron survival via TFEB dysregulation in spinal muscular atrophy” is now live on bioRxiv! Check it out here!